Authors: Ajay K. Thapar; Lucy Riglin; Rachel Blakey; Stephan Collishaw; George Davey Smith; Evie Stergiakouli; Kate Tilling; Anita Thapar · Research
Can Childhood ADHD Problems Lead to Heart Disease Risk in Middle Age?
This study examines links between childhood ADHD symptoms and cardiovascular risk factors at age 44-45 in a UK population cohort.
Source: Thapar, A. K., Riglin, L., Blakey, R., Collishaw, S., Smith, G. D., Stergiakouli, E., Tilling, K., & Thapar, A. (2023). Childhood attention-deficit hyperactivity disorder problems and mid-life cardiovascular risk: prospective population cohort study. The British Journal of Psychiatry, 223(3), 472-477. https://doi.org/10.1192/bjp.2023.90
What you need to know
- Children with ADHD symptoms had higher blood pressure, body mass index, and triglyceride levels at age 44-45 compared to those without ADHD symptoms
- Those with childhood ADHD symptoms were more likely to be smokers in middle age
- These findings suggest individuals with ADHD may benefit from cardiovascular risk monitoring and early prevention efforts
The Link Between Childhood ADHD and Adult Heart Health
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition that typically begins in childhood. While ADHD is well-known to be associated with challenges in areas like education and mental health, less is known about its potential long-term impacts on physical health.
This study set out to examine whether having ADHD symptoms in childhood might be linked to cardiovascular disease risk factors in middle age. The researchers used data from a large UK study that has followed participants from birth in 1958 all the way into adulthood.
How Was the Study Conducted?
The study looked at 8,016 people who were part of the National Child Development Study in the UK. When the participants were 7 years old, their parents and teachers filled out questionnaires about ADHD-related behaviors like being “squirmy or fidgety” and having difficulty settling. The researchers used these ratings to identify children who showed signs of ADHD problems.
Then, when the participants reached age 44-45, they underwent health assessments that measured several cardiovascular risk factors:
- Blood pressure
- Body mass index (BMI)
- Cholesterol and triglyceride levels
- Smoking status
The researchers compared these health measures between the group that had childhood ADHD symptoms and those who did not.
Key Findings on Cardiovascular Risk Factors
The study found that people who had ADHD symptoms as children showed higher levels of several cardiovascular risk factors by middle age compared to those without childhood ADHD symptoms:
- Higher body mass index (BMI): On average, the ADHD group had a BMI that was about 1 point higher
- Higher blood pressure: Systolic blood pressure was about 3.5 mmHg higher and diastolic was 2.2 mmHg higher in the ADHD group
- Higher triglyceride levels: The ADHD group had triglyceride levels that were 0.24 mmol/L higher on average
- More likely to smoke: The odds of being a current smoker were 1.6 times higher in the ADHD group
Interestingly, there was no significant difference in LDL cholesterol levels between the groups.
What Do These Results Mean?
These findings suggest that having ADHD symptoms in childhood may increase the risk of developing certain cardiovascular risk factors by middle age. This is important because these risk factors - like high blood pressure, obesity, high triglycerides, and smoking - are known to increase the chances of developing heart disease later in life.
It’s worth noting that this study shows a link between childhood ADHD and these risk factors, but it doesn’t prove that ADHD directly causes them. There could be other factors involved that weren’t measured in this study.
Why Might ADHD Be Linked to Cardiovascular Risk?
There are a few potential reasons why ADHD might be associated with higher cardiovascular risk:
Lifestyle factors: People with ADHD may be more likely to engage in behaviors like unhealthy eating or smoking that can increase cardiovascular risk.
Stress: The challenges of living with ADHD over many years could lead to chronic stress, which can affect heart health.
Shared genetic or environmental factors: There may be some underlying factors that increase the risk of both ADHD and cardiovascular problems.
Medication effects: While not a factor in this study (as ADHD medications were not widely used when these participants were children), some ADHD medications can affect heart rate and blood pressure.
Implications for ADHD Care and Heart Disease Prevention
This research highlights the importance of considering physical health, particularly cardiovascular health, in the long-term care of individuals with ADHD. Here are some key takeaways:
Cardiovascular risk monitoring: Adults with a history of ADHD may benefit from more frequent cardiovascular health check-ups.
Early prevention: Addressing modifiable risk factors like diet, exercise, and smoking could be especially important for those with ADHD.
Awareness: Both healthcare providers and individuals with ADHD should be aware of this potential increased cardiovascular risk.
Holistic care: This study underscores the need to consider both mental and physical health in the long-term management of ADHD.
Limitations of the Study
While this study provides valuable insights, it’s important to note some limitations:
- The study used a broad definition of ADHD based on a few symptoms, not a full clinical diagnosis.
- The study couldn’t account for all factors that might influence cardiovascular health over a lifetime.
- Some participants dropped out of the study over time, which could potentially affect the results.
Conclusions
- Childhood ADHD symptoms were associated with higher levels of several cardiovascular risk factors in middle age
- These findings suggest a need for increased awareness and monitoring of cardiovascular health in individuals with ADHD
- Early prevention efforts targeting modifiable risk factors may be beneficial for those with ADHD
- Further research is needed to understand the mechanisms linking ADHD and cardiovascular risk and to develop targeted prevention strategies
This study adds to growing evidence that ADHD is not just a disorder of behavior and attention, but may have far-reaching effects on physical health throughout life. By understanding these long-term risks, we can work towards better, more comprehensive care for individuals with ADHD across the lifespan.