Authors: Behrang Mahjani; Lotta Renström Koskela; Christina Gustavsson Mahjani; Magdalena Janecka; Anita Batuure; Christina M. Hultman; Abraham Reichenberg; Joseph D. Buxbaum; Olof Akre; Dorothy E. Grice · Research
How Are ADHD and Bladder Problems Connected in Children?
A systematic review finds children with ADHD are nearly 3 times more likely to have bladder and urinary issues.
Source: Mahjani, B., Koskela, L. R., Mahjani, C. G., Janecka, M., Batuure, A., Hultman, C. M., Reichenberg, A., Buxbaum, J. D., Akre, O., & Grice, D. E. (2020). Systematic Review and Meta-Analysis: Relationships Between Attention-Deficit/Hyperactivity Disorder and Daytime Urinary Symptoms in Children. medRxiv. https://doi.org/10.1101/2020.08.28.20183541
What you need to know
- Children with ADHD are almost 3 times more likely to have lower urinary tract symptoms (LUTS) compared to children without ADHD.
- The severity of ADHD symptoms is associated with more severe urinary symptoms in children.
- Younger children tend to have more urinary symptoms than older children.
The link between ADHD and bladder problems in children
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children, affecting about 5-9% of kids. The core symptoms involve ongoing patterns of inattention and/or hyperactivity-impulsivity that interfere with daily functioning. While ADHD is primarily considered a behavioral disorder, research shows it often occurs alongside other medical conditions - including problems with urination and bladder control.
This systematic review and meta-analysis examined the relationship between ADHD and lower urinary tract symptoms (LUTS) in children. LUTS refers to a range of problems related to storing and passing urine, such as:
- Urinary urgency (sudden, intense need to urinate)
- Urinary frequency (needing to urinate often)
- Daytime urinary incontinence (accidental urine leakage during the day)
- Overactive bladder syndrome
The researchers conducted a comprehensive search of medical studies looking at both ADHD and urinary symptoms in children. After screening over 100 articles, they identified 17 relevant studies to analyze in-depth. Five of these studies had enough comparable data to be combined in a meta-analysis.
Key findings on ADHD and urinary symptoms
The meta-analysis revealed that children diagnosed with ADHD were nearly 3 times more likely to have lower urinary tract symptoms compared to children without ADHD. Specifically, the odds of having LUTS were 2.99 times higher in kids with ADHD.
Several studies found that children with ADHD scored significantly higher on standardized measures of urinary symptoms compared to control groups without ADHD. For example:
- In one study of 62 children with ADHD and 124 controls, the mean total LUTS score was 11.1 for the ADHD group versus only 3.2 for controls.
- Another study of boys ages 6-12 found those with ADHD had a mean score of 14.83 on a urinary symptom scale, compared to 6.00 for controls.
Importantly, the severity of ADHD symptoms appeared to correlate with the severity of urinary symptoms. Children with more severe ADHD tended to have worse bladder control issues.
Age and gender differences
The review highlighted some interesting findings related to age and gender:
- Younger children generally had higher scores on measures of urinary symptoms compared to older children.
- Results were mixed regarding gender differences. Some studies found boys had more urinary symptoms, while others found no significant differences between boys and girls.
Types of urinary problems linked to ADHD
The most common urinary issues associated with ADHD were:
- Urinary urgency
- Urinary frequency
- Daytime urinary incontinence
- Overactive bladder syndrome
Voiding problems (difficulty emptying the bladder completely) were also reported in some studies.
Interestingly, different subtypes of urinary incontinence showed varying connections to behavioral issues. For example, children who tended to postpone urinating had the highest rates of ADHD and other psychiatric conditions.
ADHD rates in children with urinary problems
Several large population studies examined how common ADHD was among children with urinary symptoms:
- In a study of over 8,000 children, those with daytime wetting had much higher rates of attention and activity problems (24.8%) compared to children without wetting issues.
- A German study of over 2,300 children found that 10.3% of those with urinary incontinence had ADHD.
- Another German study reported ADHD symptoms in 16.8% of children with urinary incontinence, versus only 3.4% of children without incontinence.
Studies looking at children in urology clinics consistently found ADHD to be the most common psychiatric diagnosis, occurring in about 13-16% of patients. This is higher than the general population rate of around 9%.
Why are ADHD and bladder problems linked?
While this review clearly demonstrates a connection between ADHD and urinary symptoms in children, it does not explain the reasons behind this link. There are a few potential explanations that need further research:
Shared neurobiological factors: The brain regions and neurotransmitter systems involved in attention and impulse control may also play a role in bladder control.
Behavioral factors: Children with ADHD may be more likely to ignore bodily signals to use the bathroom or have trouble breaking away from activities to urinate.
Medication effects: Some ADHD medications could potentially impact urinary function as a side effect.
Overlapping risk factors: There may be common genetic or environmental risk factors that increase likelihood of both ADHD and bladder control issues.
Conclusions
- Children with ADHD have significantly higher rates of lower urinary tract symptoms compared to children without ADHD.
- The severity of ADHD symptoms correlates with the severity of urinary problems.
- ADHD is the most common psychiatric diagnosis in children seeking treatment for urinary issues.
This research highlights the importance of screening children with ADHD for potential urinary problems, and vice versa. Recognizing and addressing both conditions together may lead to more effective treatment and better quality of life for affected children.
Future studies are needed to better understand the mechanisms connecting ADHD and bladder dysfunction, as well as to develop optimal strategies for assessing and treating these co-occurring issues in children.