Authors: David Coghill; Tobias Banaschewski; Samuele Cortese; Philip Asherson; Daniel Brandeis; Jan Buitelaar; David Daley; Marina Danckaerts; Ralf W. Dittmann; Manfred Doepfner; Maite Ferrin; Chris Hollis; Martin Holtmann; Santosh Paramala; Edmund Sonuga-Barke; César Soutullo; Hans-Christoph Steinhausen; Saskia Van der Oord; Ian C K Wong; Alessandro Zuddas; Emily Simonoff · Research

How Can ADHD in Children and Adolescents Be Most Effectively Managed?

A comprehensive overview of the current evidence and best practices for managing ADHD in children and adolescents, including medication, behavioral interventions, and considerations for clinical care.

Source: Coghill, D., Banaschewski, T., Cortese, S., Asherson, P., Brandeis, D., Buitelaar, J., ... & Simonoff, E. (2023). The management of ADHD in children and adolescents: bringing evidence to the clinic: perspective from the European ADHD Guidelines Group (EAGG). European Child & Adolescent Psychiatry, 32(8), 1337-1361.

What you need to know

  • ADHD is a common neurodevelopmental disorder that can significantly impact quality of life and daily functioning for children and adolescents.
  • Both medication and behavioral interventions can be effective for managing ADHD symptoms, but long-term effectiveness data is limited.
  • Treatment should be individualized based on symptom severity, comorbid conditions, patient/family preferences, and treatment targets.

Understanding ADHD and Its Impact

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity that interferes with daily functioning and development. It affects about 5% of children and adolescents worldwide.

ADHD can have significant negative impacts on many areas of life, including:

  • Poor educational outcomes
  • Increased risk of injuries and accidents
  • Family conflict
  • Higher rates of criminal behavior
  • Comorbid mental health and physical health conditions

The total societal costs of ADHD are substantial, estimated at over $800 per capita annually in one Australian study.

Evidence for ADHD Treatments

Medication

Stimulant medications like methylphenidate and amphetamines have the strongest evidence for reducing core ADHD symptoms in the short-term. Non-stimulants like atomoxetine and guanfacine are also effective but may have slightly lower effect sizes.

Key points about ADHD medication:

  • Generally safe and well-tolerated in the short-term
  • Can improve symptoms, functioning, and quality of life
  • Long-term effectiveness and safety less well-established
  • Common side effects include decreased appetite, sleep issues, and mild increases in heart rate/blood pressure

Behavioral Interventions

Parent training programs have good evidence for improving parenting skills and reducing behavioral problems, though effects on core ADHD symptoms are less clear.

Other behavioral interventions like cognitive training and neurofeedback have shown some promise but currently have limited evidence of effectiveness for core ADHD symptoms.

Combined Treatment

Using both medication and behavioral interventions together may provide additional benefits for some patients compared to either treatment alone.

Translating Evidence into Clinical Practice

While research evidence is important, treatment plans should be individualized based on:

  • Symptom severity and impairment
  • Presence of co-occurring conditions
  • Patient and family preferences
  • Specific treatment goals and targets

Key principles for effective ADHD management include:

  • Providing psychoeducation to patients and families
  • Shared decision-making between clinicians, patients, and parents
  • Regular monitoring of symptoms, functioning, and side effects
  • Adjusting treatment as needed to optimize outcomes

Improving Access to Care

Many barriers can limit access to appropriate ADHD care, including:

  • Shortage of trained mental health providers
  • Complex referral pathways
  • Limited service availability
  • Stigma and lack of awareness

Potential strategies to improve access include:

  • Expanding use of telemedicine
  • School-based interventions
  • Community-based and digital/online treatment delivery models
  • Better integration of ADHD care in primary care settings

Conclusions

ADHD is a common and impairing condition, but effective treatments are available. Medication and behavioral interventions can significantly improve symptoms and functioning for many children and adolescents with ADHD. However, treatment should be individualized and regularly monitored. Ongoing research is needed to better understand long-term outcomes and develop improved interventions. Expanding access to evidence-based care remains an important priority.

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