Authors: Alexander Häge; Kenneth K. C. Man; Sarah K. Inglis; Jan Buitelaar; Sara Carucci; Marina Danckaerts; Ralf W. Dittmann; Bruno Falissard; Peter Garas; Chris Hollis; Kerstin Konrad; Hanna Kovshoff; Elizabeth Liddle; Suzanne McCarthy; Antje Neubert; Peter Nagy; Eric Rosenthal; Edmund J. S. Sonuga-Barke; Alessandro Zuddas; Ian C. K. Wong; David Coghill; Tobias Banaschewski · Research

How Does Long-Term ADHD Medication Affect Sleep in Children and Teens?

A comprehensive two-year study examining the effects of ADHD medication on sleep patterns in children and adolescents.

Source: Häge, A., Man, K. K. C., Inglis, S. K., Buitelaar, J., Carucci, S., Danckaerts, M., ... & Banaschewski, T. (2024). Methylphenidate and Sleep Difficulties in Children and Adolescents With ADHD: Results From the 2-Year Naturalistic Pharmacovigilance ADDUCE Study. Journal of Attention Disorders, 28(5), 699-707. https://doi.org/10.1177/10870547241232337

What you need to know

  • Children with ADHD commonly experience sleep problems, whether they take medication or not
  • Long-term use of methylphenidate (a common ADHD medication) does not appear to worsen sleep problems
  • Sleep difficulties should be monitored before and during ADHD treatment

Understanding Sleep and ADHD

If you’re a parent of a child with ADHD, you may worry about how ADHD medications might affect your child’s sleep. This is a valid concern, as sleep problems are common in children with ADHD, and some medications can potentially impact sleep patterns. However, new research provides reassuring evidence about the long-term effects of ADHD medication on sleep.

The Research Study

Researchers conducted a comprehensive two-year study following over 1,400 children and teenagers across Europe. They divided participants into three groups:

  • Children with ADHD who started taking methylphenidate (MPH)
  • Children with ADHD who didn’t take medication
  • Children without ADHD (control group)

The study used a validated sleep questionnaire that parents completed, measuring various aspects of sleep including how long it took children to fall asleep, whether they resisted bedtime, and if they experienced sleep disturbances during the night.

Key Findings About Sleep and ADHD

Before starting treatment, both groups of children with ADHD (whether they were going to take medication or not) showed more sleep problems than children without ADHD. This finding confirms what many parents and clinicians observe - that sleep difficulties are often part of living with ADHD, independent of medication use.

The researchers found that children’s sleep patterns typically didn’t worsen when taking methylphenidate long-term. In fact, some aspects of sleep actually improved over the two-year period for children taking medication, including:

  • Overall sleep quality
  • Bedtime resistance
  • Sleep-related anxiety or fears

What About Long-Term Medication Effects?

One of parents’ biggest concerns is whether ADHD medication might cause lasting sleep problems. The study found no evidence that long-term use of methylphenidate led to worsening sleep problems. When comparing the medicated and non-medicated ADHD groups over two years, researchers found:

  • No significant differences in overall sleep quality
  • Similar patterns of improvement in certain sleep behaviors
  • No emergence of new sleep problems

What This Means for You

If you’re considering ADHD medication for your child, these findings suggest that concerns about long-term sleep problems shouldn’t be a barrier to trying medication. However, it’s important to:

  1. Discuss any existing sleep problems with your healthcare provider before starting medication
  2. Monitor sleep patterns when beginning treatment
  3. Keep track of any changes in sleep habits
  4. Work with your provider to adjust medication timing or dosage if sleep issues arise
  5. Maintain good sleep hygiene practices regardless of medication status

Conclusions

  • Sleep problems are common in children with ADHD, whether or not they take medication
  • Long-term use of methylphenidate doesn’t appear to worsen sleep problems and may even help some aspects of sleep
  • Individual responses vary, so monitoring sleep patterns and working closely with healthcare providers remains important
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