Authors: James R. Latronica; Taylor J. Clegg; Wen-Jan Tuan; Curtis Bone · Research

Can ADHD Medications Increase Heart Risks in Older Adults?

Research shows common ADHD medications may pose increased cardiovascular risks for adults over 65 years old

Source: Latronica, J. R., Clegg, T. J., Tuan, W. J., & Bone, C. (2021). Are Amphetamines Associated with Adverse Cardiovascular Events Among Elderly Individuals?. The Journal of the American Board of Family Medicine, 34(6), 1074-1081.

What you need to know

  • Adults over 65 taking amphetamine medications for ADHD may have significantly higher risks of cardiovascular events compared to those not taking these medications
  • The increased risks include heart failure, stroke, irregular heart rhythms, and other heart-related complications
  • While these medications are generally safe in younger populations, older adults may be more vulnerable to their cardiovascular effects

The Growing Use of ADHD Medications in Older Adults

Picture this: You’re in your late 60s and struggling with focus and attention. Your doctor suggests trying an ADHD medication that has helped millions of younger people. But should you approach this decision differently because of your age?

This is an increasingly common scenario as ADHD medication use among older adults has risen dramatically in recent years. While these medications have a strong safety record in children and younger adults, new research suggests we need to be more cautious about their use in older populations.

Understanding the Risks

The study examined over 13,000 adults aged 65 and older who had ADHD. Researchers compared those taking amphetamine medications to those who weren’t, looking specifically at cardiovascular events like heart problems and stroke.

The findings were striking: Older adults taking amphetamines were about six times more likely to experience adverse cardiovascular events compared to those not taking these medications. This increased risk applied to various types of heart problems, including:

  • Heart failure
  • Irregular heart rhythms
  • Stroke
  • Heart disease

Why Age Matters

Our cardiovascular system changes as we age in ways that might make us more vulnerable to stimulant medications:

  • Blood vessels become less flexible
  • Heart tissue changes become less elastic
  • The heart’s electrical system works less efficiently
  • Blood pressure regulation becomes more challenging

These natural aging processes may explain why older adults might react differently to these medications than younger people do.

What’s Different About This Study

Earlier research on ADHD medications mostly focused on younger populations or included only small numbers of older adults. This study is important because it:

  • Specifically targeted adults over 65
  • Included a large number of participants (13,233 people)
  • Gathered data from 40 different healthcare organizations
  • Used careful methods to control for other factors that might affect heart health

What This Means for You

If you’re over 65 and taking or considering ADHD medication:

  1. Don’t stop taking prescribed medications without consulting your healthcare provider
  2. Have regular check-ups to monitor your blood pressure and heart health
  3. Be aware of symptoms that might indicate heart problems, such as:
    • Chest pain or pressure
    • Irregular heartbeat
    • Unusual shortness of breath
    • Dizziness or fainting
  4. Discuss alternative treatment options with your healthcare provider if you have concerns

Conclusions

  • While ADHD medications can be effective treatments, older adults may face higher cardiovascular risks when using them
  • The decision to use these medications should involve careful consideration of both benefits and risks, especially for those with existing heart concerns
  • Regular monitoring of heart health is crucial for older adults taking these medications
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