Authors: Lucy Riglin; Robyn E Wootton; Lucy A Livingston; Jessica Agnew-Blais; Louise Arseneault; Rachel Blakey; Sharifah Shameem Agha; Kate Langley; Stephan Collishaw; Michael C O'Donovan; George Davey Smith; Evie Stergiakouli; Kate Tilling; Anita Thapar · Research
Can ADHD Symptoms First Appear in Adulthood?
New research investigates whether ADHD can first emerge in adulthood and how it compares to childhood-onset ADHD.
Source: Riglin, L., Wootton, R. E., Livingston, L. A., Agnew-Blais, J., Arseneault, L., Blakey, R., Agha, S. S., Langley, K., Collishaw, S., O'Donovan, M. C., Davey Smith, G., Stergiakouli, E., Tilling, K., & Thapar, A. (2022). 'Late-onset' ADHD symptoms in young adulthood: is this the same as child-onset ADHD?. Journal of Attention Disorders, 26(10), 1271-1282. https://doi.org/10.1177/10870547211066486
What you need to know
- Some people may first develop symptoms of ADHD in adolescence or adulthood rather than childhood
- Parent-reported late-onset ADHD appears similar to childhood-onset ADHD in terms of genetic risk and cognitive difficulties
- People with late-onset ADHD tend to have more childhood resources that may have delayed symptom onset
- Self-reported late-onset ADHD appears different from childhood-onset ADHD and requires further research
A New Perspective on ADHD Onset
Attention-deficit/hyperactivity disorder (ADHD) has long been considered a condition that begins in childhood, with symptoms appearing before age 12. However, recent research has challenged this view, suggesting that some people may first develop ADHD symptoms in adolescence or adulthood. This phenomenon, known as “late-onset ADHD,” has sparked debate in the scientific community.
A new study published in the Journal of Attention Disorders set out to investigate the nature of late-onset ADHD and how it compares to the more traditional childhood-onset form of the disorder. The researchers wanted to determine if late-onset ADHD is truly the same condition as childhood ADHD, just with a delayed appearance of symptoms, or if it may represent a different disorder altogether.
How the Study Was Conducted
The research team analyzed data from the Avon Longitudinal Study of Parents and Children (ALSPAC), a large ongoing study that has followed thousands of children born in southwest England in the early 1990s. They looked at ADHD symptoms in these individuals from childhood through young adulthood, around age 25.
To get a comprehensive picture, the researchers used different methods to identify late-onset ADHD:
- They looked at symptom questionnaires completed by parents and the individuals themselves.
- They used statistical techniques to group people into different ADHD trajectory patterns over time.
- They examined both brief screening questionnaires and more detailed ADHD symptom assessments.
The study compared those with late-onset ADHD to individuals with childhood-onset ADHD that persisted into adulthood, as well as to those without ADHD. They looked at several factors, including:
- Genetic risk for ADHD
- Cognitive abilities related to attention and inhibition
- Childhood resources like verbal ability, reading skills, and family socioeconomic status
- Risk factors for depression
Key Findings on Late-Onset ADHD
The study uncovered several important findings about late-onset ADHD:
Prevalence of Late-Onset ADHD
The researchers found that between 5-14% of young adults showed signs of late-onset ADHD, depending on how it was measured. This suggests that late-onset ADHD may be relatively common.
Genetic Risk
When late-onset ADHD was identified based on parent reports, these individuals showed similar levels of genetic risk for ADHD as those with childhood-onset ADHD. This suggests that parent-reported late-onset ADHD may have a similar genetic basis as the childhood-onset form.
Cognitive Difficulties
Again, when based on parent reports, people with late-onset ADHD showed similar cognitive difficulties in areas of attention and inhibition as those with childhood-onset ADHD. This further supports the idea that parent-reported late-onset ADHD may be similar to the childhood-onset form.
Childhood Resources
Interestingly, individuals with late-onset ADHD tended to have higher levels of certain childhood resources compared to those with childhood-onset ADHD. These resources included:
- Better verbal ability
- Stronger reading skills
- Higher family income
- Higher maternal education
This finding suggests that these resources may have helped compensate for or mask ADHD symptoms earlier in life, potentially explaining the later onset of noticeable symptoms.
Gender Differences
Late-onset ADHD was more common in females compared to childhood-onset ADHD, which tends to be more prevalent in males. However, there was not a clear female predominance in late-onset ADHD overall.
Depression Risk Factors
The study did not find strong evidence that late-onset ADHD was associated with risk factors for depression. This suggests that late-onset ADHD is likely not simply a misclassification of depression symptoms.
Self-Reported vs. Parent-Reported Late-Onset ADHD
An important finding of this study was the difference between self-reported and parent-reported late-onset ADHD:
- Parent-reported late-onset ADHD appeared similar to childhood-onset ADHD in terms of genetic risk and cognitive difficulties.
- Self-reported late-onset ADHD showed some key differences from childhood-onset ADHD:
- Lower genetic risk for ADHD
- Better cognitive performance
- Identified a larger group of individuals
These differences highlight the need for further research to understand the nature of self-reported late-onset ADHD and whether it may represent a different phenomenon than parent-reported late-onset ADHD.
Implications and Future Directions
This study provides important insights into the nature of late-onset ADHD:
It supports the idea that ADHD can truly emerge for the first time in adolescence or adulthood for some individuals.
Parent-reported late-onset ADHD appears to be similar to childhood-onset ADHD in many ways, suggesting it may be the same underlying condition with delayed symptom onset.
Higher childhood resources may help explain why some individuals don’t show noticeable ADHD symptoms until later in life.
Self-reported late-onset ADHD requires further investigation, as it may represent a different phenomenon than parent-reported late-onset ADHD.
The findings challenge the current diagnostic criteria for ADHD, which require symptom onset before age 12.
Future research should continue to investigate the similarities and differences between late-onset and childhood-onset ADHD. In particular, more work is needed to understand self-reported late-onset ADHD and its relationship to the more established forms of the disorder.
Additionally, studies should examine whether current ADHD treatments are equally effective for those with late-onset ADHD. If late-onset ADHD truly represents the same condition as childhood-onset ADHD, similar treatments may be beneficial. However, if there are meaningful differences, treatment approaches may need to be tailored for this group.
Conclusions
- Late-onset ADHD appears to be a real phenomenon, with symptoms first emerging in adolescence or adulthood for some individuals.
- Parent-reported late-onset ADHD shares many similarities with childhood-onset ADHD, including genetic risk and cognitive difficulties.
- Higher childhood resources may help explain delayed symptom onset in some individuals with ADHD.
- Self-reported late-onset ADHD shows some key differences from childhood-onset ADHD and requires further investigation.
- These findings challenge current diagnostic criteria and highlight the need for a more nuanced understanding of ADHD across the lifespan.
As our understanding of ADHD continues to evolve, it’s clear that the disorder is more complex than previously thought. Recognizing that ADHD can emerge later in life is an important step toward better identifying and supporting all individuals affected by this condition.